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Article

Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.

Oncotarget - 1 Aug 2010

Duncan Christopher G, Killela Patrick J, Payne Cathy A, Lampson Benjamin, Chen William C, Liu Jeff, Solomon David, Waldman Todd, Towers Aaron J, Gregory Simon G, McDonald Kerrie L, McLendon Roger E, Bigner Darell D, Yan Hai

Abstract excerpt

The glioblastoma genome displays remarkable chromosomal aberrations, which harbor critical glioblastoma-specific genes contributing to several oncogenetic pathways. To identify glioblastoma-targeted genes, we completed a multifaceted genome-wide analysis to characterize the most significant aberrations of DNA content occurring in glioblastomas. We performed copy number analysis of 111 glioblastomas by Digital...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, Tumor Suppressor

Share to Glioblastoma

Share to Microtubule-Associated Proteins

Share to Oncogenes

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21113414
DOI: 10.18632/oncotarget.137
PMCID: PMC2992381

Genes

ERRFI1
TACC3
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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