Article
Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility - a prospective, translational study.
Molecular oncology - 1 Nov 2020
Nørøxe Dorte S, Yde Christina W, Østrup Olga, Michaelsen Signe R, Schmidt Ane Y, Kinalis Savvas, Torp Mathias H, Skjøth-Rasmussen Jane, Brennum Jannick, Hamerlik Petra, Poulsen Hans S, Nielsen Finn C, Lassen Ulrik
Abstract excerpt
Glioblastoma (GBM) is an incurable brain tumor for which new treatment strategies are urgently needed. Next-generation sequencing of GBM has most often been performed retrospectively and on archival tissue from both diagnostic and relapse surgeries with limited knowledge of clinical information, including treatment given. We sought to investigate the genomic composition prospectively in treatment-naïve patients,...
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