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Studying a Complex Tumor

1 Jan 2012

Abstract excerpt

Glioblastoma multiforme is a histopathologically heterogeneous disease with few treatment options. Therapy based on genomic alterations is rapidly gaining popularity because of the high response rate and high specificity. DNA copy number and exon-sequencing studies of glioblastoma multiforme samples have revealed recurrent genomic alterations in genes such as TP53, EGFR, and IDH1, but to date, this has not...

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PMID: 22290264
DOI: 10.1097/ppo.0b013e3182431c57

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