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Article

Sensorimotor gating in NTS1 and NTS2 null mice: effects of d-amphetamine, dizocilpine, clozapine and NT69L.

The Journal of experimental biology - 15 Dec 2010

Oliveros Alfredo, Heckman Michael G, Del Pilar Corena-McLeod Maria, Williams Katrina, Boules Mona, Richelson Elliott

Abstract excerpt

Pre-pulse inhibition (PPI) of the acoustic startle reflex is deficient in patients with schizophrenia. This deficiency is mimicked in mice by the use of the psychotomimetic drugs d-amphetamine and dizolcipine. Antipsychotic drugs such as clozapine are used to treat schizophrenic patients and are also administered to mice to prevent PPI disruption. Neurotensin (NT) produces antipsychotic-like effects when injected...

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Identifiers

PMID: 21113004
DOI: 10.1242/jeb.046318
PMCID: PMC2992465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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