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Article

Does genetic BDNF deficiency in rats interact with neurotransmitter control of prepulse inhibition? Implications for schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Apr 2017

van den Buuse Maarten, Biel Davina, Radscheit Kathrin

Abstract excerpt

Several studies have suggested a role of BDNF in the development of schizophrenia. For example, post-mortem studies have shown significantly reduced levels of BDNF protein expression in the brain of schizophrenia patients. We investigated the relationship between reduced levels of BDNF in the brain and the regulation of prepulse inhibition (PPI), a behavioral endophenotype of schizophrenia. We used BDNF...

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Identifiers

PMID: 28192174
DOI: 10.1016/j.pnpbp.2017.02.009

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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