Associations of rs3740677 within GAB2 Gene with LOAD in Chinese Han Population.

doi:10.1007/s12035-016-9953-8

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Article

Associations of rs3740677 within GAB2 Gene with LOAD in Chinese Han Population.

Molecular neurobiology - 1 Aug 2017

Zheng Jing-Yu, Wang Hui-Fu, Wan Yu, Tan Meng-Shan, Tan Chen-Chen, Tan Lin, Zhang Wei, Zheng Zhan-Jie, Kong Ling-Li, Wang Zi-Xuan, Tan Lan, Yu Jin-Tai

Abstract excerpt

GRB2-associated binding protein 2 (GAB2) has been identified as a crucial factor in Alzheimer's disease (AD), and ten common variants within GAB2 have been detected to be associated with AD onset risk in genome-wide association studies (GWAS). Here, we first screened a common locus (rs3740677) in 3' UTR of GAB2 sequence which is targeted by the miRNA-185 and initiatively explored the probable associations of...

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Identifiers

PMID: 27311772
DOI: 10.1007/s12035-016-9953-8

Genes

GAB2
APOE
GRB2

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