Article
Calcineurin-dependent galactomannan release in Aspergillus fumigatus.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Apr 2011
Mennink-Kersten M A S H, Ruegebrink D, Verweij P E, Steinbach W J
Abstract excerpt
The galactomannan assay to diagnose invasive aspergillosis is recommended and clinically utilized, yet the mechanism of galactomannan release from Aspergillus fumigatus is unknown. We used an A. fumigatus strain lacking calcineurin A (cnaA), already shown to be critically important for pathogenicity, to evaluate galactomannan kinetics. During the logarithmic growth phase when glucose was consumed,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
