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Article

Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus.

Antimicrobial agents and chemotherapy - 1 Feb 2009

Fortwendel Jarrod R, Juvvadi Praveen Rao, Pinchai Nadthanan, Perfect B Zachary, Alspaugh J Andrew, Perfect John R, Steinbach William J

Abstract excerpt

Aspergillus fumigatus must be able to properly form hyphae and maintain cell wall integrity in order to establish invasive disease. Ras proteins and calcineurin each have been implicated as having roles in these processes. Here, we further delineate the roles of calcineurin and Ras activity in ce...

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Identifiers

PMID: 19015336
DOI: 10.1128/AAC.01154-08
PMCID: PMC2630655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19015336-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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