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Understanding Aspergillus fumigatus galactosaminogalactan biosynthesis: A few questions remain

7 Jan 2023

Abstract excerpt

Half a century after their discovery, polymers of N-acetylgalactosamine produced by the Aspergilli have garnered new interest as mediators of fungal virulence. Recent work has focused on the Aspergillus fumigatus secreted and cell wall-associated heteropolymer, galactosaminogalactan (GAG). This polymer, composed of galactose (Gal) and partially deacetylated N-acetylgalactosamine (GalNAc), plays a role in a...

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PMID: 36691652
DOI: 10.1016/j.tcsw.2023.100095

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