N-acetylglucosamine affects Cryptococcus neoformans cell-wall composition and melanin architecture.

doi:10.1099/mic.0.000552

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Article

N-acetylglucosamine affects Cryptococcus neoformans cell-wall composition and melanin architecture.

Microbiology (Reading, England) - 1 Nov 2017

Camacho Emma, Chrissian Christine, Cordero Radames J B, Liporagi-Lopes Livia, Stark Ruth E, Casadevall Arturo

Abstract excerpt

Cryptococcus neoformans is an environmental fungus that belongs to the phylum Basidiomycetes and is a major pathogen in immunocompromised patients. The ability of C. neoformans to produce melanin pigments represents its second most important virulence factor, after the presence of a polysaccharide capsule. Both the capsule and melanin are closely associated with the fungal cell wall, a complex structure that is...

Topics

Acetylglucosamine
Cell Wall
Chitin
Chitosan
Cryptococcus neoformans
Drug Resistance, Fungal
Enzyme Assays
Laccase
Melanins
Microbial Sensitivity Tests
Phenotype

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PMID: 29043954
DOI: 10.1099/mic.0.000552
PMCID: PMC5775898

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