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Article

Dynamics of in vitro fitness recovery of HIV-1.

Journal of virology - 1 Feb 2011

Lorenzo-Redondo Ramón, Bordería Antonio V, Lopez-Galindez Cecilio

Abstract excerpt

The study on the evolutionary consequences of an RNA viral population's fluctuations can be approached by in vitro experiments. This work describes the fitness recovery of HIV-1 after 20 large-population passages in 10 debilitated clones. The serial passages promoted an increase in viral fitness. In addition, we detected a significant number of mutations fixed in the complete genome consensus sequence of the...

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Share to gag Gene Products, Human Immunodeficiency Virus
Share to Genome, Viral
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to HIV Envelope Protein gp120

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Share to RNA, Viral

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Source

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Identifiers

PMID: 21106747
DOI: 10.1128/JVI.01254-10
PMCID: PMC3028893

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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