Article
Influence of mutation and recombination on HIV-1 in vitro fitness recovery.
Molecular phylogenetics and evolution - 1 Jan 2016
Arenas Miguel, Lorenzo-Redondo Ramon, Lopez-Galindez Cecilio
Abstract excerpt
The understanding of the evolutionary processes underlying HIV-1 fitness recovery is fundamental for HIV-1 pathogenesis, antiretroviral treatment and vaccine design. It is known that HIV-1 can present very high mutation and recombination rates, however the specific contribution of these evolutionary forces in the "in vitro" viral fitness recovery has not been simultaneously quantified. To this aim, we analyzed...
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