Article
Following the very initial growth of biological RNA viral clones.
The Journal of general virology - 1 Feb 2005
Cuevas José M, Moya Andrés, Sanjuán Rafael
Abstract excerpt
Due to their extremely high genetic diversity, which is a direct consequence of high mutation rates, RNA viruses are often described as molecular quasispecies. According to this theory, RNA virus populations cannot be understood in terms of individual viral clones, as they are clouds of interconnected mutants, but this prediction has not yet been demonstrated experimentally. The goal of this study was to...
Topics
- Animals
- Biological Evolution
- Cell Line
- Models, Biological
- Mutation
- RNA, Viral
- Selection, Genetic
- Species Specificity
- Vesicular stomatitis Indiana virus