Article
Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in Type 1 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 2010
Currie D, McKnight A J, Patterson C C, Sadlier D M, Maxwell A P
Abstract excerpt
BACKGROUND: Polymorphisms in ACE and AGTR1 genes have been assessed in multiple studies for association with diabetic nephropathy; however, results are conflicting. The ACE2 gene has not been studied extensively for association with diabetic nephropathy. METHODS: We investigated variants in ACE, ACE2 and AGTR1 for association with nephropathy in a case-control group (1467 participants with Type1 diabetes, case...
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