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Article

Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome.

Journal of medical genetics - 1 Apr 2011

Talseth-Palmer Bente A, Brenne Ingvild S, Ashton Katie A, Evans Tiffany-Jane, McPhillips Mary, Groombridge Claire, Suchy Janina, Kurzawski Grzegorz, Spigelman Allan, Lubinski Jan, Scott Rodney J

Abstract excerpt

OBJECTIVE: Recently, six colorectal cancer (CRC) susceptibility loci have been identified, and two single-nucleotide polymorphisms (SNPs)--rs16892766 (8q23.3) and rs3802842 (11q23.1)--from two of these regions have been found to be significantly associated with an increased CRC risk in patients with Lynch syndrome. The objective of this study was to genotype nine SNPs within these six loci to confirm previous...

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Identifiers

PMID: 21097774
DOI: 10.1136/jmg.2010.079962

Genes

MLH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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