Article
Colorectal cancer susceptibility loci on chromosome 8q23.3 and 11q23.1 as modifiers for disease expression in Lynch syndrome.
Journal of medical genetics - 1 Apr 2011
Talseth-Palmer Bente A, Brenne Ingvild S, Ashton Katie A, Evans Tiffany-Jane, McPhillips Mary, Groombridge Claire, Suchy Janina, Kurzawski Grzegorz, Spigelman Allan, Lubinski Jan, Scott Rodney J
Abstract excerpt
OBJECTIVE: Recently, six colorectal cancer (CRC) susceptibility loci have been identified, and two single-nucleotide polymorphisms (SNPs)--rs16892766 (8q23.3) and rs3802842 (11q23.1)--from two of these regions have been found to be significantly associated with an increased CRC risk in patients w...
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