Article
Meta association of colorectal cancer confirms risk alleles at 8q24 and 18q21.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2009
Curtin Karen, Lin Wei-Yu, George Rina, Katory Mark, Shorto Jennifer, Cannon-Albright Lisa A, Bishop D Timothy, Cox Angela, Camp Nicola J
Abstract excerpt
BACKGROUND: Genome-wide association studies of colorectal cancer (CRC) have identified genetic variants that reproducibly associate with CRC. Associations of 12 single nucleotide polymorphisms at 8q24, 9p24, and 18q21 (SMAD7) and CRC were investigated in a three-center collaborative study including two U.K. case-control cohorts (Sheffield and Leeds) and a U.S. case-control study of CRC cases from high-risk Utah...
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