Article
Ek alpha transgene in B10 mice suppresses the development of myasthenia gravis.
Immunogenetics - 1 Jan 1990
Christadoss P, David C S, Shenoy M, Keve S
Abstract excerpt
Mice bearing the H-2b haplotype are susceptible to the development of experimental autoimmune myasthenia gravis (EAMG), induced by acetylcholine receptor (AChR) autoimmunity. One of the genes influencing EAMG susceptibility has been mapped to the Ab locus of the major histocompatibility complex, and the A beta chain has been implicated in the pathogenesis. Mice of the H-2b haplotype, including C57BL/10 (B10),...
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