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Article

Genetic deficiency of estrogen receptor alpha fails to influence experimental autoimmune myasthenia gravis pathogenesis.

Journal of neuroimmunology - 1 May 2011

Qi Huibin, Li Jing, Allman Windy, Saini Shamsher S, Tüzün Erdem, Wu Xiaorong, Estes D Mark, Christadoss Premkumar

Abstract excerpt

Autoimmune myasthenia gravis (MG) is characterized by T cell and antibody responses to muscle nicotinic acetylcholine receptor (AChR). It is well known that MG as other autoimmune diseases is more prevalent in women than men and estrogen administration enhances experimental autoimmune MG (EAMG) severity. To determine whether estrogen influences EAMG pathogenesis through estrogen receptor alpha (ERα) activation,...

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Identifiers

PMID: 21481948
DOI: 10.1016/j.jneuroim.2011.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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