Article
Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 1999
Zhang G X, Xiao B G, Bai X F, van der Meide P H, Orn A, Link H
Abstract excerpt
IFN-gamma can either adversely or beneficially affect certain experimental autoimmune diseases. To study the role of IFN-gamma in the autoantibody-mediated experimental autoimmune myasthenia gravis (EAMG), an animal model of myasthenia gravis in humans, IFN-gammaR-deficient (IFN-gammaR-/-) mutant C57BL/6 mice and congenic wild-type mice were immunized with Torpedo acetylcholine receptor (AChR) plus CFA....
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