Article
The effect of B cell deficiency on the immune response to acetylcholine receptor and the development of experimental autoimmune myasthenia gravis.
Clinical immunology and immunopathology - 1 Jun 1998
Dedhia V, Goluszko E, Wu B, Deng C, Christadoss P
Abstract excerpt
To study the involvement of B cells in the immune response to acetylcholine receptor (AChR), B-cell-deficient (mu mutant) and control wild-type C57BL/6 mice were immunized with AChR and assessed for clinical and immunopathological manifestations of experimental autoimmune myasthenia gravis (EAMG)...
Topics
- Animals
- Antibodies
- Antibody Formation
- Antibody Specificity
- B-Lymphocytes
- Cytokines
- Epitopes
- Immunization, Passive
- Interferon-gamma
- Lymphocyte Activation
- Lymphocyte Count
- Macrophages
- Mice
- Mice, Inbred C57BL
- Mutation
- Myasthenia Gravis
- Receptors, Cholinergic
- T-Lymphocytes