Article
Rab1 GTPase regulates phenotypic modulation of pulmonary artery smooth muscle cells by mediating the transport of angiotensin II type 1 receptor under hypoxia.
The international journal of biochemistry & cell biology - 1 Mar 2011
Yin Hongjin, Li Qi, Qian Guisheng, Wang Yaoli, Li Yuncheng, Wu Guangyu, Wang Guansong
Abstract excerpt
Previous studies have demonstrated that Rab1 is involved in the export of angiotensin II (Ang II) type 1 receptor (AT1R) to the cell surface in endothelial cells and cardiomyocytes. The aim of this study was to evaluate whether the modification of Rab1-mediated endoplasmic reticulum (ER) to the G...
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