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Article

Involvement of Rho GTPases and their regulators in the pathogenesis of hypertension

13 May 2014

Abstract excerpt

Proper regulation of arterial blood pressure is essential to allow permanent adjustment of nutrient and oxygen supply to organs and tissues according to their need. This is achieved through highly coordinated regulation processes controlling vascular resistance through modulation of arterial smooth muscle contraction, cardiac output, and kidney function. Members of the Rho family of small GTPases, in particular...

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Identifiers

PMID: 25496262
DOI: 10.4161/sgtp.28846

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