D2 receptor genotype and striatal dopamine signaling predict motor cortical activity and behavior in humans.

doi:10.1016/j.neuroimage.2010.11.034

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Article

D2 receptor genotype and striatal dopamine signaling predict motor cortical activity and behavior in humans.

NeuroImage - 14 Feb 2011

Fazio Leonardo, Blasi Giuseppe, Taurisano Paolo, Papazacharias Apostolos, Romano Raffaella, Gelao Barbara, Ursini Gianluca, Quarto Tiziana, Lo Bianco Luciana, Di Giorgio Annabella, Mancini Marina, Popolizio Teresa, Rubini Giuseppe, Bertolino Alessandro

Abstract excerpt

OBJECTIVE: Pre-synaptic D2 receptors regulate striatal dopamine release and DAT activity, key factors for modulation of motor pathways. A functional SNP of DRD2 (rs1076560 G>T) is associated with alternative splicing such that the relative expression of D2S (mainly pre-synaptic) vs. D2L (mainly p...

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Identifiers

PMID: 21087673
DOI: 10.1016/j.neuroimage.2010.11.034

Genes

DRD2
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Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21087673-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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