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Article

Dynamic epigenetic enhancer signatures reveal key transcription factors associated with monocytic differentiation states.

Blood - 14 Jun 2012

Pham Thu-Hang, Benner Christopher, Lichtinger Monika, Schwarzfischer Lucia, Hu Yuhui, Andreesen Reinhard, Chen Wei, Rehli Michael

Abstract excerpt

Cellular differentiation is orchestrated by lineage-specific transcription factors and associated with cell type-specific epigenetic signatures. In the present study, we used stage-specific, epigenetic "fingerprints" to deduce key transcriptional regulators of the human monocytic differentiation process. We globally mapped the distribution of epigenetic enhancer marks (histone H3 lysine 4 monomethylation, histone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22550342
DOI: 10.1182/blood-2012-01-402453

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EGR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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