Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy.

Cancer research - 15 Jun 1995

Hongyo T, Buzard G S, Palli D, Weghorst C M, Amorosi A, Galli M, Caporaso N E, Fraumeni J F, Rice J M

Abstract excerpt

K-ras and p53 gene mutations in intestinal-type gastric carcinomas from a high-incidence area around Florence, Italy, were studied by single strand conformation polymorphism and DNA sequencing analysis. Single-strand conformation polymorphism analysis of K-ras indicated aberrant bands in 13 of 34 cases. Sequencing revealed point mutations in 7 (including two at a previously unreported site in codon 11), a...

Topics

Adenocarcinoma
Alleles
Base Sequence
DNA Primers
DNA, Neoplasm
Europe
Exons
Genes, p53
Genes, ras
Geography
Helicobacter Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Helicobacter pylori

Humans

Immunohistochemistry

Incidence

Italy

Japan

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7780983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7780983-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations of the K-ras and p53 genes in gastric adenocarcinomas from a high-incidence region around Florence, Italy.PMID 7780983Read ↗

Diet, Helicobacter pylori, and p53 mutations in gastric cancer: a molecular epidemiology study in Italy.Semantic proximity Read ↗

Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China.Semantic proximity Read ↗

Mutations of p53 in gallbladder carcinomas in high-incidence areas of Japan and Chile.Semantic proximity Read ↗

P53 mutations in colorectal cancer from northern Iran: Relationships with site of tumor origin, microsatellite instability and K-ras mutations.Semantic proximity Read ↗

Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area.Semantic proximity Read ↗

p53 mutations in esophageal tumors from high-incidence areas of China.Semantic proximity Read ↗

Analysis of p53, K-ras gene mutation & Helicobacter pylori infection in patients with gastric cancer & peptic ulcer disease at a tertiary care hospital in north India.Semantic proximity Read ↗

CagA status of Helicobacter pylori infection and p53 gene mutations in gastric adenocarcinoma.Semantic proximity Read ↗

High frequency of TP53 but not K-ras gene mutations in Bolivian patients with gallbladder cancer.Semantic proximity Read ↗

Implication of K-ras and p53 in colorectal cancer carcinogenesis in Tunisian population cohort.Semantic proximity Read ↗

p53 alterations but no human papillomavirus infection in preinvasive and advanced squamous esophageal cancer in Italy.Semantic proximity Read ↗

Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and country of origin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.