Article
Rapid single nucleotide polymorphism mapping in C. elegans.
BMC genomics - 12 Sept 2005
Davis M Wayne, Hammarlund Marc, Harrach Tracey, Hullett Patrick, Olsen Shawn, Jorgensen Erik M
Abstract excerpt
BACKGROUND: In C. elegans, single nucleotide polymorphisms (SNPs) can function as silent genetic markers, with applications ranging from classical two- and three-factor mapping to measuring recombination across whole chromosomes. RESULTS: Here, we describe a set of 48 primer pairs that flank SNPs evenly spaced across the C. elegans genome and that work under identical PCR conditions. Each SNP in this set alters a...
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