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Article

The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress.

The Journal of biological chemistry - 31 Dec 2010

Clausing Emanuel, Mayer Andreas, Chanarat Sittinan, Müller Barbara, Germann Susanne M, Cramer Patrick, Lisby Michael, Strässer Katja

Abstract excerpt

Multiple DNA-associated processes such as DNA repair, replication, and recombination are crucial for the maintenance of genome integrity. Here, we show a novel interaction between the transcription elongation factor Bur1-Bur2 and replication protein A (RPA), the eukaryotic single-stranded DNA-binding protein with functions in DNA repair, recombination, and replication. Bur1 interacted via its C-terminal domain...

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Identifiers

PMID: 21075850
DOI: 10.1074/jbc.M110.193292
PMCID: PMC3009894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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