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Article

Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APP Tg2576 mouse model of Alzheimer's disease.

Neurobiology of learning and memory - 1 Jan 2011

Bardgett Mark E, Davis Natasha N, Schultheis Patrick J, Griffith Molly S

Abstract excerpt

Previous research has indicated that the blockade of H(3)-type histamine receptors may improve attention and memory in normal rodents. The purpose of this study was to determine if ciproxifan, an H(3) receptor antagonist, could alleviate the hyperactivity and cognitive deficits observed in a tran...

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Identifiers

PMID: 21073971
DOI: 10.1016/j.nlm.2010.10.008
PMCID: PMC3034295

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21073971-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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