Article
Quetiapine modulates conditioned anxiety and alternation behavior in Alzheimer's transgenic mice.
Current Alzheimer research - 1 Feb 2013
Tempier Adrien, He Jue, Zhu Shenghua, Zhang Ruiguo, Kong Lynda, Tan Qingrong, Luo Huanmin, Kong Jiming, Li Xin-Min
Abstract excerpt
Quetiapine, an atypical antipsychotic drug, is effective in treating the behavioral and psychological symptoms in Alzheimer's disease (AD). However, it is presently unclear whether quetiapine has beneficial effects on memory and whether the effects of quetiapine on psychological symptoms are associated with its effect on memory in AD. The present study was designed to examine the effect of chronic administration...
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