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Article

Molecular determination of RHD zygosity: predicting risk of hemolytic disease of the fetus and newborn related to anti-D.

Prenatal diagnosis - 1 Dec 2010

Pirelli Kevin J, Pietz Bradley C, Johnson Susan T, Pinder Holly L, Bellissimo Daniel B

Abstract excerpt

OBJECTIVE: Development of an accurate molecular method for paternal RHD zygosity to predict risk to a fetus for hemolytic disease of the fetus and newborn (HDFN) related to anti-D. METHODS: Quantitative fluorescence polymerase chain reaction (QF-PCR) was used to detect RHD exons 5 and 7, using RHCE exon 7 as an internal control. The genotype and zygosity were determined from the peak area ratios of RHD exon 5 or...

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Source

Identifiers

PMID: 21072752
DOI: 10.1002/pd.2652

Genes

RHD
RHCE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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