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Article

A real-time PCR-based noninvasive prenatal RHD screening assay optimized for population-specific RHD allelic spectra in China.

BMC medical genomics - 8 Aug 2026

Wei Xiang, Jiang Linzhi, Zhu Qian

Abstract excerpt

BACKGROUND: Prenatal RhD screening enables risk stratification for RhD-associated hemolytic disease of the fetus and newborn (HDFN) and supports rational，evidence-based use of prophylactic anti-RhD immunoglobulin. However, noninvasive prenatal RhD screening remains challenging in the Chinese population, primarily due to population-specific RHD allelic diversity and the limited adaptability of current assay...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42571004
DOI: 10.1186/s12920-026-02337-2
PMCID: PMC13452092

Genes

RHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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