RHD genotyping from maternal plasma: guidelines and technical challenges.

doi:10.1007/978-1-59745-066-9_14

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Article

RHD genotyping from maternal plasma: guidelines and technical challenges.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Avent Neil D

Abstract excerpt

Rhesus D (RhD) blood group incompatibility between mother and fetus can occasionally result in maternal alloimmunization where the resultant anti-D can cross the placenta and attack the fetal red cells, which in worse case scenarios can cause fetal anemia and ultimately death. Fetal RHD genotyping was introduced in the mid-1990s after the molecular characterization of the RH genes as an aid to the clinical...

Topics

DNA
Female
Gene Expression Regulation, Developmental
Genetic Testing
Genotype
Humans
Polymerase Chain Reaction
Practice Guidelines as Topic
Predictive Value of Tests
Pregnancy
Prenatal Diagnosis
Reproducibility of Results
Rh Isoimmunization
Rh-Hr Blood-Group System

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Open in PubMed

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PMID: 18425481
DOI: 10.1007/978-1-59745-066-9_14

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