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Article

Rapid RHD Zygosity Determination Using Digital PCR.

Clinical chemistry - 1 Aug 2017

Sillence Kelly A, Halawani Amr J, Tounsi Wajnat A, Clarke Kirsty A, Kiernan Michele, Madgett Tracey E, Avent Neil D

Abstract excerpt

BACKGROUND: Paternal zygosity testing is used for determining homo- or hemizygosity of RHD in pregnancies that are at a risk of hemolytic disease of the fetus and newborn. At present, this is achieved by using real-time PCR or the Rhesus box PCR, which can be difficult to interpret and unreliable, particularly for black African populations. METHODS: DNA samples extracted from 53 blood donors were analyzed using 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28615230
DOI: 10.1373/clinchem.2016.268698

Genes

RHD
AGO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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