Article
Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response.
Psychiatric genetics - 1 Feb 2011
Wu Gui-Sheng, Luo Huai-Rong, Dong Chuanhui, Mastronardi Claudio, Licinio Julio, Wong Ma-Li
Abstract excerpt
OBJECTIVE: Melanocortin 1 receptor (MC1R) is involved in various functions, such as pigmentation, antipyretic and anti-inflammatory actions, development of melanoma, susceptibility to ultraviolet-induced sun damage, modification of oculocutaneous albinism, development of freckles, and mediation of female-specific mechanisms of analgesia. MC1R's natural agonists include α-melanocyte-stimulating hormone and...
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