Article
Computational modeling of constitutively active mutants of GPCRs C5a receptor.
Methods in enzymology - 1 Jan 2010
Nikiforovich Gregory V, Baranski Thomas J
Abstract excerpt
In the past decade, an increasing number of studies using computational modeling procedures have focused on the structural aspects of constitutive activity in G protein-coupled receptors (GPCRs). This chapter reviews various conceptual approaches in computational modeling of constitutively active...
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