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Article

3D modeling of the activated states of constitutively active mutants of rhodopsin.

Biochemical and biophysical research communications - 23 Jun 2006

Nikiforovich Gregory V, Marshall Garland R

Abstract excerpt

The activated (R*) states in constitutively active mutants (CAMs) of G-protein-coupled receptors (GPCRs) are presumably characterized by lower energies than the resting (R) states. If specific configurations of TM helices differing by rotations along the long transmembrane axes possess energies lower than that in the R state for pronounced CAMs, but not for non-CAMs, these particular configurations of TM helices...

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Identifiers

PMID: 16682009
DOI: 10.1016/j.bbrc.2006.04.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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