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Article

IL28B SNP rs8099917 is strongly associated with pegylated interferon-α and ribavirin therapy treatment failure in HCV/HIV-1 coinfected patients.

PloS one - 29 Oct 2010

Aparicio Ester, Parera Mariona, Franco Sandra, Pérez-Alvarez Nuria, Tural Cristina, Clotet Bonaventura, Martínez Miguel Angel

Abstract excerpt

Recent genome-wide association studies report that the SNP rs8099917, located 8.9 kb upstream of the start codon of IL28B, is associated with both disease chronicity and therapeutic response to pegIFN-α and RBV in patients infected with genotype 1 HCV. To determine the effect of rs8099917 variati...

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Identifiers

PMID: 21048934
DOI: 10.1371/journal.pone.0013771
PMCID: PMC2966433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21048934-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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IL28B SNP rs8099917 is strongly associated with pegylated interferon-α and ribavirin therapy treatment failure in HCV/HIV-1 coinfected patients.PMID 21048934Read ↗

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