Article
Relationship between IL28B gene rs8099917 polymorphism and SVR in Turkish patients with hepatitis C virus genotype 1.
Clinics and research in hepatology and gastroenterology - 1 Dec 2015
Akkız Hikmet, Akgöllü Ersin, Bekar Aynur, Yıldırım Selçuk, Sandıkçı Macit, Ülger Yakup, Yalınbaş Kaya Berrin, Kuran Sedef, Üsküdar Oğuz
Abstract excerpt
BACKGROUND AND OBJECTIVE: The hepatitis C virus (HCV) which infects 3% of the world's population is a global challenge. Recently, genome-wide association studies (GWAS) have identified that the IL28B gene rs8099917 polymorphism was associated with the response to the pegylated-interferon alpha/ribavirin (PegIFNα/RBV) combination therapy in patients infected with HCV genotype 1. IL28B gene rs8099917 polymorphism...
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