Article
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 11 Jun 2008
Xie Zhong, Photowala Huzefa, Cahill Michael E, Srivastava Deepak P, Woolfrey Kevin M, Shum Cassandra Y, Huganir Richard L, Penzes Peter
Abstract excerpt
Remodeling of central excitatory synapses is crucial for synapse maturation and plasticity, and contributes to neurodevelopmental and psychiatric disorders. Remodeling of dendritic spines and the associated synapses has been postulated to require the coordination of adhesion with spine morphology and stability; however, the molecular mechanisms that functionally link adhesion molecules with regulators of...
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