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Carbonylated proteins are eliminated during reproduction in C. elegans

7 Sept 2010

Abstract excerpt

Oxidatively damaged proteins accumulate with age in many species (Stadtman (1992) Science257, 1220-1224). This means that damage must be reset at the time of reproduction. To visualize this resetting in the roundworm Caenorhabditis elegans, a novel immunofluorescence technique that allows the detection of carbonylated proteins in situ was developed. The application of this technique revealed that carbonylated...

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PMID: 21040398
DOI: 10.1111/j.1474-9726.2010.00625.x

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