Article
Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration.
Journal of neurochemistry - 1 Dec 2010
Peng Jun, Oo May Lin, Andersen Julie K
Abstract excerpt
As Parkinson's disease appears to be a multifactoral disorder, the use of animal models to investigate combined effects of genetic and environmental risk factors are of great importance especially in the context of aging which is the single major risk factor for the disorder. Here, we assessed the combined effects of neonatal iron feeding and environmental paraquat exposure on age-related nigrostriatal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
