Article
Interactions between environmental and genetic factors in the pathophysiology of Parkinson's disease.
IUBMB life - 1 Jun 2003
Tsang Fai, Soong Tuck Wah
Abstract excerpt
Parkinson's disease (PD) is a progressive neurodegenerative disease with no known cure and affects approximately 1% of the elderly population. The major question in PD relates to the selective loss of dopaminergic neurons in patients. The underlying mechanism of genetic dysfunction and environmental toxins in contributing to the pathogenesis of PD may be oxidative stress. The interactions of genetic and...
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