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Article

Concordant analysis of KRAS status in primary colon carcinoma and matched metastasis.

Anticancer research - 1 Oct 2010

Mariani Pascale, Lae Marick, Degeorges Armelle, Cacheux Wulfran, Lappartient Emmanuelle, Margogne Audrey, Pierga Jean-Yves, Girre Véronique, Mignot Laurent, Falcou Marie Christine, Salmon Rémy-Jacques, Delattre Olivier, De Cremoux Patricia

Abstract excerpt

KRAS somatic mutations are the main predictive factor for non response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer (mCRC) patients. We compared KRAS mutational status in the primary tumour and the corresponding metastases (1 to 4 sites) in 38 mCRC patients. KRAS mutatio...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21036746

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21036746-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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