Article
Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer.
BMC cancer - 9 Aug 2012
Kim Mi-Jung, Lee Hye Seung, Kim Jee Hyun, Kim Yu Jung, Kwon Ji Hyun, Lee Jeong-Ok, Bang Soo-Mee, Park Kyoung Un, Kim Duck-Woo, Kang Sung-Bum, Kim Jae-Sung, Lee Jong Seok, Lee Keun-Wook
Abstract excerpt
BACKGROUND: We evaluated the association between a KRAS mutational status and various clinicopathologic features including the metastatic pattern in patients with metastatic or recurrent colorectal cancer (MRCRC). The concordance rates of the KRAS status between primary tumor sites and paired metastatic organs were also analyzed. METHODS: The KRAS mutational status in codons 12, 13, and 61 from formalin-fixed...
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