Article
Molecular differences in the KRAS gene mutation between a primary tumor and related metastatic sites - case report and a literature review.
Folia histochemica et cytobiologica - 1 Dec 2010
Kosakowska Ewa Anna, Stec Rafał, Charkiewicz Radosław, Skoczek Marta, Chyczewski Lech
Abstract excerpt
In recent years the the set of diagnostic tools in colorectal cancers has been extended by the assessment of the KRAS gene status. Currently it is a necessary step in order to qualify patients for the targeted therapy. The results of the analysis of several studies revealed a high rate of compliance of the KRAS gene mutational status in primary and metastatic tumors. In this paper we present a rare case of...
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