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Article

Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14.

Proceedings of the National Academy of Sciences of the United States of America - 9 Nov 2010

Luebben Whitney R, Sharma Neelam, Nyborg Jennifer K

Abstract excerpt

Histone posttranslational modifications and chromatin dynamics are inextricably linked to eukaryotic gene expression. Among the many modifications that have been characterized, histone tail acetylation is most strongly correlated with transcriptional activation. In Metazoa, promoters of transcriptionally active genes are generally devoid of physically repressive nucleosomes, consistent with the contemporaneous...

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Share to Acetyl Coenzyme A
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20974913
DOI: 10.1073/pnas.1009650107
PMCID: PMC2984149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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