Article
[H2A.Z: a histone variant that decorates gene promoters].
Medecine sciences : M/S - 1 Nov 2006
Guillemette Benoît, Gaudreau Luc
Abstract excerpt
The nucleosome, fundamental unit of chromatin, is composed of four basic histones, H2A, H2B, H3 and H4, around which DNA is wrapped. In order to have access to DNA, cells must modify the structure of chromatin by different known mechanisms. One such mechanism is by replacing canonical histones in the nucleosome with variants, which can confer special functions to chromatin. H2A.Z is an evolutionary conserved...
Topics
- Chromatin
- DNA
- Gene Expression Regulation, Fungal
- Genetic Variation
- Heterochromatin
- Histones
- Promoter Regions, Genetic
- Transcription, Genetic