Article
Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning.
PLoS biology - 1 Dec 2005
Guillemette Benoît, Bataille Alain R, Gévry Nicolas, Adam Maryse, Blanchette Mathieu, Robert François, Gaudreau Luc
Abstract excerpt
H2A.Z is an evolutionary conserved histone variant involved in transcriptional regulation, antisilencing, silencing, and genome stability. The mechanism(s) by which H2A.Z regulates these various biological functions remains poorly defined, in part due to the lack of knowledge regarding its physical location along chromosomes and the bearing it has in regulating chromatin structure. Here we mapped H2A.Z across the...
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