Article
Genetic variation in the androgen estrogen conversion pathway in relation to breast cancer prognosticators.
Breast cancer research and treatment - 1 Jun 2011
Darabi Hatef, Czene Kamila, Wedrén Sara, Li Yuqing, Liu Jianjun, Hall Per, Humphreys Keith
Abstract excerpt
Genetic variation in the androgen-to-estrogen conversion pathway has been shown to be associated with risk of breast cancer and, in particular, with estrogen receptor (ER) positive tumours. We aimed at studying how the genetic alterations, which have been identified for risk, are associated with breast cancer prognosticators, with a prior hypothesis that, in general, hormone-related breast cancers have a better...
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