Article
Genetic polymorphisms of the CYP19A1 gene and breast cancer survival.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2006
Long Ji-Rong, Kataoka Nobuhiko, Shu Xiao-Ou, Wen Wanqing, Gao Yu-Tang, Cai Qiuyin, Zheng Wei
Abstract excerpt
The CYP19A1 protein (aromatase) plays a critical role in estrogen biosynthesis and thus may be related to the progression of breast cancer. We examined the association between CYP19A1 genetic polymorphisms and breast cancer survival in a cohort of 1,136 patients who were recruited as part of a population-based case-control study in Shanghai, China from 1996 to 1998 and who has donated a DNA sample to the study....
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